It's the year 1590 (Tensho 18 in the Japanese era). After the demise of warlord Nobunaga Oda, Japan was about to be unified by Hideyoshi Toyotomi. However, one man in Kanto is defiant to it. He calls himself TenmaOh (Mirai MORIYAMA) and leads the Kanto Dokuro-To, an armed group hiding in the pitch-black Dokuro-Jo (skull castle). Sutenosuke (Shun Oguri) happens to rescue a woman who has been chased by the Kanto Dokuro-To. To hide and shelter the woman, Sutenosuke meets Mukaiya Ranbe (Taichi Saotome) at a brothel district. Manipulated by magical fate, people start to congregate in the Kanto region. When the shared past between Sutenosuke and Ranbe, and the relation to TenmaOh come to light, TenmaOh's dark ambition is about to be revealed. With just seven souls, Sutenosuke sets out to destroy the Dokuro-Jo, which is surrounded by 20,000 soldiers.